it makes Focusing your DPS onto any target that can stand the beam for longer than 1 second Very easy. With all 3 people using the Beam rifle there is no question who is attacking what. When you have 3 people with that, With Armor Piercing mods, Also with a Fully upgraded Ammo Power on Each of your 3 characters, Basically nothing can stand up to it. The key to this setup is The Prothean Beam Rifle that you earn from the DLC mission to Recruit Javik. You CAN throw Javik in their as well, because he can use the Assault Rifle, However he does lack Ammo powers, But his Biotics Can more than make up for it just in case Unshielded Trash makes its way to you.
Add Garrus and Ashley to the mix as well, Also Toting Assault Rifles and Ammo powers. The best setup is to have Your Shepard with a Assault Rifle, Any kind of Ammo power, And whatever else compliments his Class well. Mass Effect 3 Shep/Garrus/Ashley Beam rifle Party Setup, Best crew in the whole game for Campaign :)